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KMID : 0984720030350050321
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Infection and Chemotherapy
2003 Volume.35 No. 5 p.321 ~ p.324
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A Case of Disseminated Fusarium Infection Treated by Liposomal Amphotericin B in a Leukemic Patient
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Lee Ji-Yeon
Kim Sung-Bum
Park Dae-Won
Shin Sung-Hee
Kim Yong-Hyun
Yoon So-Young
Eom Joong-Sik
Choi Chul-Won
Cheong Hee-Jin
Kim Woo-Joo
Kim Jun-Suk
Kim Jang-Su
Lee Kap-No
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Abstract
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Fusarium spp., basically a superficial pathogen, is a newly emerging fungal pathogen of opportunistic infections in immunocompromised patients. At present, although Fusarium spp. are relatively resistant to amphotericin B, the combination of amphotericin B and surgical debridement appear to be optimal treatment for disseminated infection. Recently we experienced a 32yearold neutropenic patient after induction chemotherapy for acute myelocytic leukemia presented with skin lesions and infiltrations in both lungs. We diagnosed with disseminated fusariosis by skin culture and successfully treated the patient with Liposomal amphotericin B. We emphasize a high index of suspicion for skin lesions especially in immunocopromised patients.
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KEYWORD
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Fusariosis, Liposomal amphotericin B, Opportunistic infection
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